NON-RANDOM PATTERN OF INTEGRATION FOR EPSTEIN-BARR VIRUS WITH PREFERENCE FOR GENE-POOR GENOMIC CHROMOSOMAL REGIONS INTO THE GENOME OF BURKITT LYMPHOMA CELL LINES

Non-Random Pattern of Integration for Epstein-Barr Virus with Preference for Gene-Poor Genomic Chromosomal Regions into the Genome of Burkitt Lymphoma Cell Lines

Background: Epstein-Barr virus (EBV) is an oncogenic virus found in about 95% of endemic Burkitt lymphoma (BL) cases.In latently infected cells, EBV DNA is mostly maintained in episomal Bandages form, but it can also be integrated into the host genome, or both forms can coexist in the infected cells.Methods: In this study, we mapped the chromosomal

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Importance of Internet Surveillance in Public Health Emergency Control and Prevention: Evidence From a Digital Epidemiologic Study During Avian Influenza A H7N9 Outbreaks

BackgroundOutbreaks of human infection with Bandages a new avian influenza A H7N9 virus occurred in China in the spring of 2013.Control and prevention of a new human infectious disease outbreak can be strongly affected by public reaction and social impact through the Internet and social media.ObjectiveThis study aimed to investigate the potential r

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